The students will solve a mystery using laboratory tests for different types of macromolecules. They will use argumentation to justify and communicate their claim. They will construct explanations and communicate with one another to determine which macromolecule would be best to eat in different scenarios. Students will be able to identify the structure and functions of the four main types of macromolecules. The students will use laboratory testing to determine the identity of an unknown. They will fill in a chart about the structures, functions, and examples for each macromolecule type and then they will practice their knowledge by answering short response questions relating the macromolecules to the real world. Finally, they will review using a whole-class cooperative activity and take a quiz about the structures and functions of macromolecules.